78 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... used to detect ANAs ... Positive ANA ≠ Autoimmune ... The higher the ANA ... often not specific ANA
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... Antinuclear #Antibodies #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
) antibody • ANAs ... have ANAs; thus ... , a negative ANA ... B serology • ANAs ... CRP level • ANAs
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... searched for when ANA ... Association with both SLE ... higly specific for SLE ... rheumatology #table #ANA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE
Fistula-In-Ano: External opening of fistulus tract is apparent in photo above. Proximal opening would
be at level
Fistula-In-Ano: ... be at level of crypts ... , within the anal ... canal. ... #FistulaInAno #Anal
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Workup: - ANA ... Erythematosus (SLE ... Workup: - ANA ... management of SLE
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
pericarditis (search ANA ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... lupus #diagnosis #sle
Lower GI Bleed - Differential Diagnosis Algorithm

 • Structural: Diverticulosis, Hemorrhoids, Post-polypectomy, Polyps & malignancy, Anal
Differential Diagnosis Algorithm ... & malignancy, Anal ... fistula, Colonic and ... Differential #Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ) - Diagnosis and ... are evocative of SLE ... Workup: - ANA ... management of SLE