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diagnosis differential rheumatology management lupus causes erythematosus workup systemic table antinuclear treatment patterns peds pediatrics pulmonary antibodies antibody autoantibodies neurology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies (ANA ... ) ANA or Anti-NucIear ... Positive ANA ≠ Autoimmune ... • Pattern: The ANA ... Antinuclear #Antibodies #ANA
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... Antinuclear #Antibodies #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
) antibody • ANAs ... have ANAs; thus ... , a negative ANA ... B serology • ANAs ... multiple myeloma) • ANA
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... Association with both SLE ... Anti-Ribo-P 5-15% If SLE ... higly specific for SLE ... rheumatology #table #ANA
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... Non-specific; common in SLE ... RA Anti-dsDNA - SLE ... - Drug-induced SLE ... Diffuse) Anti-Sm - SLE
Fistula-In-Ano: External opening of fistulus tract is apparent in photo above. Proximal opening would be at level
Fistula-In-Ano: ... be at level of crypts ... , within the anal ... canal. ... #FistulaInAno #Anal
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Erythematosus (SLE ... are evocative of SLE ... Workup: - ANA ... management of SLE
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
pericarditis (search ANA ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... lupus #diagnosis #sle
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ) - Diagnosis and ... are evocative of SLE ... Workup: - ANA ... management of SLE
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... dysmotility • MCTD (SLE ... • Specific for SLE ... Ann Marie Kumfer ... Erythematosus #SLE
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