12 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (EGPA ... antibody) - P-ANCA ... >PR3 Renal-limited ... #CANCA #PANCA #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
-ANCA (C-ANCA): ... GPA >>> MPA > eGPA ... • MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... Glomerulonephritis #Vasculitis
Frequency of ANCA Positivity in Different Conditions
ANCA-Associated Vasculitis
 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
GPA - PR3-ANCA 75% ... • MPA - PR3-ANCA ... • EGPA - PR3- ... • Renal-limited ... vasculitis - PR3
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... ) - ANCA Vasculitis ... Management Algorithm ... #ANCA #Vasculitis ... #algorithm #rheumatology
2021 ACR/VF Guidelines for Management of Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

#Granulomatosis #Polyangiitis #GPA
Polyangiitis (GPA ... #Polyangiitis #GPA ... #ACR2021 #Management ... #rheumatology # ... algorithm #vasculitis
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Active
) - ANCA Vasculitis ... Management Algorithm ... #Polyangiitis #ANCA ... #Vasculitis #Management ... #Treatment #ACR2021
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
myeloperoxidase (MPO-ANCA ... > PR3 60% • GPA ... 100 % Commonly MPO-ANCA ... Vasculitis: + MPO-ANCA ... (Dx: GPA, EGPA,
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Vasculitis Management ... Polyangiitis (GPA ... Polyangiitis (MPA ... #ACR2021 #Guidelines ... #algorithm #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
>PR3 - ANCA+ 90% ... >MPO - ANCA+ 60% ... >PR3 - ANCA+ 30- ... vasculitis - MPO ... >PR3 - ANCA+ 10-
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... polyangiitis (GPA ... polyangiitis (eGPA ... StanfordChiefs #ANCA ... #diagnosis #algorithm