21 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC ... shift of K (Succinylcholine ... #differential #diagnosis ... #pathophysiology ... #pharmacology #
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
potassium and ECG ... blocks, QRS axis shift ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
Typical ECG ... ) BRASH Treatment ... • Aggressive treatment ... BRASH #Syndrome #diagnosis ... #management #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... : No • Treatment ... Reactions #hematology #diagnosis ... #comparison #table
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
and menses • Pathophysiology ... Labs/lmaging: Hypokalemia ... fT4 or high T3 ... • Treatment: Potassium ... Periodic #Paralysis #diagnosis
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Dialysis for severe hyperkalemia ... #Differential #Diagnosis
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... densa receives high ... #pharmacology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment: ... Induction Rx: high-dose
Hyperkalemia Management
Pseudohyperkalemia: 1. Hemolyzed sample 2. Blood drawn from a site/line where potassium or TPN is
Hyperkalemia Management ... minutes-hour) -Shift ... @AnnKumfer #Hyperkalemia ... #Management #treatment ... #potassium #high