14 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... loss through the nephron ... #Pharmacology # ... nephrology #conversion ... loop #thiazide #classes
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
associated with hypokalemia ... - Shift from extracellular ... - Insulin (high ... differential #diagnosis #nephrology ... #Causes #hypomg
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... of High-anion Gap ... Generalized distal nephron ... Potassium-sparing diuretics ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • K sparing diuretics ... Intracellular Shift ... differential #diagnosis #causes ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Causes of Hypokalemia ... Transcellular shift ... contracted • Loop diuretics ... syndrome • Thiazide diuretics ... #Nephrology #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • K sparing diuretics ... Intracellular Shift ... differential #diagnosis #causes ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... Weakness, cramping, nausea ... only if no clear cause ... Terbutaline 7 µg/kg ... Treatment #potassium #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... ; High-Ceiling Diuretics ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... #Nephrology #Pharmacology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... through distal nephron ... • Low EABV (e.g ... • NSAlDs #Hyperkalemia ... IntercellularShift #Nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... Shift of extracellular ... Loop diuretics for ... #nephrology