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diagnosis differential management causes algorithm nephrology potassium treatment hypokalemia neurology cardiology high signs symptoms endocrinology medications oncology ecg electrocardiogram lysis
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Hypocalcemia • Hyperkalemia ... #TLS #Pathophysiology
Hypercalcemia - EKG Findings Causes of Hypercalcemia • Malignancy • Milk-alkali syndrome • Vitamin D toxicity •
Hypercalcemia - ... EKG Findings Causes ... of Hypercalcemia ... • Milk-alkali syndrome ... #EKG #ECG #Electrocardiogram
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... - Refeeding Syndrome ... #Hypokalemia ... potassium #low #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... • Refeeding syndrome ... Transcellular shifts ... MatthewHoMD #Hypokalemia
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... Laboratory TLS ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... clinical scenario, ECG ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
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