13 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... with Ca only if EKG ... #Syndrome #TLS ... #oncology #management
Emergency Management of Hyperkalemia in Adults
Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach
 •
Management of Hyperkalemia ... guided by clinical ... scenario, ECG and ... Gluconate IV Shift ... recurrence #Hyperkalemia
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Calcium ≤ 7.0 mg/dL Clinical ... hydroxide • Hyperkalemia ... diagnosis #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... #Syndrome #diagnosis ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... Low calcium • Treatment ... hydration - Hyperkalemia ... treatment (no calcium ... unless worrisome EKG
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Cancer Related • Hypercalcemia ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... syndrome • Proximal ... #AKI #Cancer #Oncology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... (e.g. ... Tumor Lysis Syndrome
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Dermatomyositis Clinical ... or compartment syndrome ... Shift of extracellular ... Treatment of underlying
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... TLS (tumor-lysis ... plasmapheresis Hypercalcemia ... → no immediate treatment ... #Emergencies #Oncology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Management Summary Clinical ... Budd Chiari syndrome ... disease Imaging and Treatment ... Hypercalcemia 4 ... kinase inhibitors (e.g