51 results
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
heparin Acute Phosphate ... intake, Phosphate ... Transcellular Shift ... CKD Increased Renal ... #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
 • Decreased intake/absorption: Starvation, Alcoholism, Malabsorption, Phosphate binder use
 • Redistribution/
Malabsorption, Phosphate ... Redistribution/ Shift ... bone syndrome • Renal ... Algorithm #causes #nephrology ... #phosphate
Hyperphosphatemia - Differential Diagnosis Algorithm
Transcellular Shift:
 • Rhabdomyolysis
 • Tumor Lysis
 • Metabolic or Respiratory Acidosis
Transcellular Shift ... PO4 < 20%: • Renal ... Context of Impaired Renal ... Hypervitaminosis D • Phosphate ... Supplementation • Phosphate
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Medications Renal ... Losses Non-renal ... Transcellular shifts ... Diagnosis #Algorithm #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Fractional Excretion of Phosphate ... Transcellular Shift ... FEPO4 ≥ 5% - Renal ... Framework #Workup #phosphate ... #nephrology
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... 2,3-DPG which shifts ... , condition of renal ... -DPG causing a shift ... respiratory #hypoxia #pathophysiology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low Kidney Phosphate ... Diarrhea, Antacids, Phosphate ... Transcellular Shift ... Inappropriately High Kidney Phosphate ... Diagnosis #Algorithm #nephrology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment of renal ... hyperparathyroidism Phosphate ... Calcium-containing phosphate ... #Pharmacology #Pathophysiology
Renal osteodystrophy: Pathogenesis and radiological features.

#Renal #Osteodystrophy #Pathophysiology #Nephrology
Renal osteodystrophy ... #Renal #Osteodystrophy ... #Pathophysiology ... #Nephrology
Renal Tubular Disorders

 • Distal Renal Tubular Acidosis (Type 1)
 • Proximal Renal Tubular Acidosis (Type
Renal Tubular Disorders ... • Distal Renal ... ) • Proximal Renal ... Acidosis #Types #pathophysiology ... #nephrology #diagnosis