51 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Proteinuria often ... #Nephrology #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... hematuria and/or proteinuria ... nephrotic/nephritic syndromes ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
(Negative urine ... • Fanconi's syndrome ... (Positive urine ... albuminuria) - Active urine ... #Nephrology #Differential
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... • Refeeding syndrome ... Medications Renal ... Losses Non-renal ... Diagnosis #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
pain hematuria syndrome ... hematuria • Signs ... - Proteinuria ... causes #urology #nephrology ... #renal #urine #
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
of magnesium = (urine ... serum magnesium x urine ... intake, Gl loss, shift ... cells FEMg >4% = renal ... diagnosis #causes #nephrology
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
associated with worse renal ... : - Urine total ... defined as nephrotic syndrome ... classification #CKD #nephrology ... #diagnosis #proteinuria
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
WBCs, or urine ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology
Urine Specific Gravity - Interpretation
Specific Gravity = Density of urine / Density of water
SG close to
Urine Specific Gravity ... Gravity = Density of urine ... Dehydration • SIADH (syndrome ... Glycosuria • Proteinuria ... #differential #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine ... clinical context and signs ... Abdominal compartment syndrome ... syndrome: troponin ... Differential #Diagnosis #nephrology