18 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications ... #druginduced
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... Thyrotoxicosis Medications ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... Normal, Renin High ... hypoplasia Aldosterone high ... • Type 1 #Hyperkalemia ... Diagnosis #algorithm #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... Medications 2. ... #high #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... - Shift from extracellular ... - Insulin (high ... #Medications #differential ... #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... reactions Common Drugs ... Intracellular Shift ... Medications 2. ... #high #nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Acidosis Causes of High-anion ... Drug-induced hyperkalemia ... Potassium-sparing ... diagnosis #causes #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... creatinine) • Cell shift ... syndrome #hypokalemia ... #urine #potassium ... algorithm #diagnosis #nephrology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Diuretics #Medications ... #Pharmacology # ... summary #table #nephrology