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diagnosis differential hyperkalemia management hypokalemia treatment algorithm classes high hypomagnesemia hypomg low rhabdomyolysis summary table acei acidosis action aldosterone angiotensin
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
Diuretics sites ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... differential #diagnosis #nephrology ... #Causes #hypomg
Antiarrhythmic Drugs CLASS IA • Procainamide, Quinidine, Disopyramide CLASS 1B • Lidocaine, Mexiletine CLASS 2 • Propranolol, Esmolol CLASS 4
Antiarrhythmic Drugs ... Adenosine, Magnesium, Potassium ... Antiarrhythmic #Medications ... #Classes #Classification ... #Pharmacology #
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... renal disease Drugs ... #differential #medications ... #drugs #pharmacology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Piretanide Potassium ... #Pharmacology # ... nephrology #conversion ... loop #thiazide #classes
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... Conn's, Liddle's), Drugs ... #Hypokalemia #Causes ... differential #diagnosis #nephrology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
sodium, which causes ... RAAS inhibiting drug ... diuretic, which ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
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