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differential hyperkalemia management algorithm high hypokalemia hypomagnesemia treatment druginduced hypomg low rhabdomyolysis summary table acidosis acute aki aldosterone angiotensin aniongap
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... • Discontinued diuretic ... #Algorithm #nephrology ... #low #potassium
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Hypokalemia - Shift ... hypomagnesemia #Medications ... #differential #diagnosis ... #nephrology #Causes
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Angiotensin-converting enzyme (ACE ... • Increased EC shift ... #differential #diagnosis ... #potassium #medications
ACEI or ARB Initiation Hyperkalemia: - Review concurrent drugs - Moderate potassium Intake - Consider: diuretics, sodium
ACEI or ARB Initiation ... Review concurrent drugs ... - Moderate potassium ... - Review for causes ... Reassess concomitant medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should
sodium, which causes ... RAAS inhibiting drug ... , ACEI, ARB, and ... diuretic, which ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Causes of Hypomagnesemia ... - Potassium depletion ... #diagnosis #differential ... #medications #drugs ... #pharmacology #
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #causes #potassium ... #high #nephrology
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... • Dehydration: Diuretics ... autoregulation: ACEIs ... #Drugs #pharmacology ... #differential #diagnosis
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
• NSAIDs • ACE ... Intracellular Shift ... Medications 2. ... #causes #potassium ... #high #nephrology
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