25 results
diagnosis differential causes management hypokalemia algorithm treatment high table hypomagnesemia hypomg indications pathophysiology renal rhabdomyolysis summary syndrome acei acidosis action
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Transcellular Shift ... Thyrotoxicosis Medications ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology ... #low #potassium
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... Agents Subclass, Drug ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Diuretics sites of action on the nephron 1) Acetazolamide (carbonic anhydrase inhibitor) 2) Osmotic diuretics (e.g. mannitol) 3) Loop
Diuretics sites ... Metolazone) 5) Potassium-sparing ... diuretics (e.g. ... #pharmacology # ... nephrology #medications
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... with hypokalemia ... - Shift from extracellular ... #Medications #differential ... #diagnosis #nephrology
Hyperkalemia Treatment Options Stabilize cardiac membrane: • IV Calcium (peaks 5-10 minutes) Decrease potassium concentration: • IV Fluids Shift
Hyperkalemia Treatment ... • IV Fluids Shift ... function) - Loop diuretic ... LouLectures #Hyperkalemia ... #nephrology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... • Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... • K sparing diuretics ... Intracellular Shift ... Medications 2. ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
reactions Common Drugs ... • K sparing diuretics ... Intracellular Shift ... Medications 2. ... #high #nephrology
Indications for Emergent Hemodialysis Indications: "AEIOU" A - Acidosis ( pH < 7.1 ) E
- refractory hyperkalemia ... refractory to diuresis ... encephalopathy Dialyzable Drugs ... Mnemonic #AEIOU #Nephrology ... #Dialyzable #Drugs
Causes of Hypokalemia Transcellular Shifts: - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... Transcellular Shifts ... Conn's, Liddle's), Drugs ... or induced) #Hypokalemia ... differential #diagnosis #nephrology
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