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diagnosis hematology differential management oncology dermatology cancer chronic classification generalized leukemia pruritus secondary systemic thrombocytosis workup acidosis activation acute agglutinin
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... #Causes #Hematology
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... Differential Diagnosis Algorithm ... Superior vena cava syndrome ... • Anxiety • Anemia ... #Causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Dyspnea - Differential ... Diagnosis Algorithm ... Acute Coronary Syndrome ... Pulmonary - Other • Anemia ... #Causes
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... Radiation induced disease ... - Cytopenias (anemia ... Changes in Pre-Test ... #algorithm #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome ... #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... fatigue, pallor, dyspnea ... • Diagnostic Test ... Donath-Landsteiner test ... #hematology #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... value is low, tests ... result in severe anemia ... immune hemolytic anemia ... leukocytosis with a left shift
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... with leukopenia, anemia ... Liver function tests ... Treatment: • Corticosteroids ... #Rheumatology
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