29 results
diagnosis rheumatology differential syndrome dermatology lupus erythematosus vasculitis algorithm clinical neurology oncology photo primary sjogrens stills workup acute adult adultonset
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
erythematosus (SLE ... ) Signs / Symptoms ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... 69% - Malar rash ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... solid cancers • Systemic ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... characterized by extensive skin ... rash in association ... Skin involvement ... Resolution > 15 days Differentials
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... • Polymorphous rash ... - Generalized Skin ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... trauma leads to skin ... , painless, no systemic ... signs, labs normal ... biopsy preferred Differential
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