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diagnosis differential dermatology syndrome hematology lupus erythematosus symptoms systemic algorithm vasculitis joint neurology oncology syphilis blood clinical dermatomyositis disorders pain
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #rashes #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... erythematosus #signs
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Associated with skin ... • Specific for SLE ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... Skin Biopsy
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... , the differential ... includes Kawasaki disease ... erythematous rash
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar rash ... life-threatening • Treatment ... : Chronic disease ... #Summary #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Involving the Skin ... Secondary: CTD: SLE ... Vasculitis Skin ... Cutaneous #Vasculitis #skin ... #dermatology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #signs #symptoms ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs ... #rheumatology
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