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diagnosis differential vasculitis management rheumatology syndrome causes disease hyperthyroidism primary 21hydroxylasedeficiency 21ohd acromegaly algorithm arteritis behcet biliary cholangitis cirrhosis classification
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Menorrhagia - Skin ... • Skin is ... amenorrhea - Skin ... • Warm, moist skin ... #endocrinology
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... Inflammation of skin ... granulomas under skin ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
Pathogenesis and Clinical ... Negative Straight Leg ... MeralgiaParesthetica #MSK #pathophysiology ... #differential # ... diagnosis #signs
CREST Syndrome: Pathogenesis and Clinical Findings CALCINOSIS (BB-sized, hard nodules in fingers) RAYNAUD'S Phenomenon ESOPHAGEAL DYSMOTILITY SCLERODACTYLY (thickening and tightening
Pathogenesis and Clinical ... tightening of skin ... CREST #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Psoriatic Arthritis: Pathogenesis and Clinical findings In tendons and connective tissues: • Enthesitis - Pain/tenderness over
Pathogenesis and Clinical ... are inflamed In skin ... Psoriatic plaques on skin ... #diagnosis #signs ... #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
Pathogenesis and Clinical ... / Symptoms: - ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology ... #Symptoms
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Disorders #Algorithm #Differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... erythematosus #signs ... #symptoms #diagnosis
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
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