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diagnosis management differential algorithm lfts hematology gastroenterology hepatitis transaminitis cirrhosis injury nephrology syndrome workup causes chemistry chronic coccidioides coccidioidomycosis fungal
Hepatic Encephalopathy - Diagnosis and Management Summary Definition: • Alteration in brain function manifested by neuropsychiatric symptoms
• Caused by liver ... other causes of neurologic ... Initiate empiric treatment ... • Skeletal muscle ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... Hepatocellular Liver ... expression in skeletal ... #differential #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... , cardiac & skeletal ... , cardiac & skeletal ... nucleotidase - Liver ... Interpretation #diagnosis #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... - Cardiac and skeletal ... specific for the liver ... SinaiBmoreIMRes #Liver ... Transaminitis #diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Chronic hepatitis, Skeletal ... #Patterns #Liver ... #Injury #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... Identify Acute Liver ... hematoma) • AST: Skeletal ... Brain • ALT: Skeletal ... #differential #Hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... ALT: • AST: liver ... > skeletal muscle ... In liver, 80% of ... AlkPhos #Bilirubin #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... disease, liver ... support, or liver ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Causes of Acute Liver ... hematoma) • AST: Skeletal ... brain • ALT: Skeletal ... diagnosis #algorithm #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... progressing to acute liver ... Liver transplant ... Hepatobiliary #hepatology
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