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management symptoms differential syndrome dermatology erythematosus hematology lupus msk sle systemic dermatomyositis hemophagocytic hlh lymphohistiocytosis pathophysiology rheumatoid antimda5 antimda5dm antinxp2
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Shrinking lung ... syndrome - SLE Neurologic ... #differential #diagnosis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... skin injury) • Neurologic ... Behcet syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... Fever is the main clinical ... rash) • Heart, lung ... #Syndrome #Diagnosis ... #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... effusion, Restrictive lung ... of hip (rare), Arthritis ... erythematosus #signs ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... Myositis 4% - Lung ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Lyme Disease: Early and Late Clinical manifestations Stage 1. Localized • EM appears 7-14 days at the
Lyme Disease: Early ... and Late Clinical ... • Heralded by neurologic ... years after • Arthritis ... #diagnosis #signs
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Pathogenesis and clinical ... of the Hip • Arthritis ... Chondrodysplasia Neurologic ... causes #symptoms #signs ... #diagnosis #msk
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... spondylitis - Sacroiliac ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... mass and NO prior signs ... diffuse chondral disease ... #mri #clinical ... #msk #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Chronic B-cell activation ... #Rheumatology
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