24 results
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... ANCA associated vasculitis ... Systemic lupus erythematosus ... #Differential #Diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... ischemia - Skin: erythematous ... systemic lupus erythematosus ... purpura: strong sign ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Systemic lupus erythematosus ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... • Ulcerated, erythematous ... Differential Diagnosis ... dermatology #rash #diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Glomerulonephritis #Vasculitis ... #differential #diagnosis ... #algorithm #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... systemic lupus erythematosus ... classification #rheumatology