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diagnosis differential hematuria acute aki blood kidneyinjury nephritis nephrotic syndrome urology workup ain atlas biopsy clinicopathology comparison dipstick glomerular glucosuria
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Nephrology #Differential ... #Causes
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... key #diagnosis #nephrology ... #casts
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology ... if cause not identified
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... eosinophiluria, microscopic ... , mild tubular proteinuria ... , granular casts ... #nephrology #diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
sediment Microscopic ... hematuria: - RBC casts ... - Proteinuria ... microscopic and ... #urology #nephrology
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
PROBLEM ~80% of AKI cases ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, casts ... , crystals, protein
Urinalysis & Urine Sodium Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteins, documenting proteinuria ... Microscopic exam ... • Crystals ... • Urinary casts ... #UNa #casts #glucosuria
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... nephrotic range) proteinuria
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... myeloma) • Urate crystals ... polyangiitis /microscopic ... #KidneyInjury #Nephrology
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