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diagnosis differential management antinuclear arthritis autoantibodies classification disease hematology signs workup associations dermatology erythematosus lupus patterns pulmonary ra renal sle
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
ANA - Non-specific ... hepatitis Anti-CCP, Rheumatoid ... c-ANCA - Vasculitis ... granulomatosis p-ANCA ... #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Vasculitis: • ... Microscopic polyangiitis ... Jcortesizaguirr #ANA ... #diagnosis #rheumatology
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... - C-ANCA pattern ... PR3 Anti-GBM disease ... @AnnKumfer #ANCA ... PR3 #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Using fluorescence microscopy ... context of other symptoms ... Rheumatic Diseases ... • Rheumatic Diseases ... #rheumatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis: + MPO-ANCA ... Diagnosis: Systemic rheumatic ... Presentation - Systemic Symptoms ... LFT • ESR • ANA ... ) pattern: antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... others (RNP, aPL antibodies ... ribonucleoprotein) • RA: Rheumatoid ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... polyangiitis, Microscopic ... polyangiitis) - ANCA-negative ... testing: anti-ANCA ... , anti-GBM ab, ANA
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Nodosa (PAN), ANCA ... associated vasculitis ... (rare) • Rheumatic ... (IgG4-RD), Rheumatoid ... Differential #Diagnosis #rheumatology
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Scleritis, Heart Disease ... , Rheumatoid Vasculitis ... , Pulmonary Disease ... RA #diagnosis #rheumatology ... #signs #symptoms
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Vasculitis of ... small vessels - ANCA-associated ... granulomatosis - microscopic ... drugs, malignomas, and ... Vessels #Diagnosis #Rheumatology
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