27 results
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
acute kidney injury ... • Treatment includes ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis ... #management #nephrology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing Acute ... Kidney Injury ( ... sphincter tone: • Opiates ... #pharmacology # ... differential #diagnosis
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... Avoiding nephrotoxic drugs ... treating underlying cause ... appropriate) #Acute ... #Kidney #Injury
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... and Management ... Drugs (Statins), ... Treatment: 1 ... #causes #treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... /HDS treatments ... for alternative causes ... dechallenge • Acute ... #Diagnosis #Algorithm
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
Hyperthermia (most common cause ... Cornerstone of treatment ... all serotonergic drugs ... SerotoninSyndrome #management ... #toxicology #REBELEM
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... 5) History of acute ... Aspirin #Toxicity #Toxicology ... #diagnosis #management ... #Treatment
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... #diagnosis
In addition to management of ABCs, exposure to nerve gases requires antidotes. There are 3 important
are 3 important drug ... classes used in ... acute management ... #Management #Toxicology ... #NerveAgents #Treatment
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Summary Causes ... - Toxins - Drugs ... #Management #causes