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management differential aki neurology acidosis algorithm amiodarone aspirin classification clozapine dili druginduced elderly elevation encephalopathy ferrous geriatrics hepatology induced iron
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing Acute ... Kidney Injury ( ... sphincter tone: • Opiates ... #pharmacology # ... differential #diagnosis
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
• Drug induced ... acute kidney injury ... • Treatment includes ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis
Acute Iron Poisoning There are five classically described phases of toxicity: Gastrointestinal phase (~6 hours post-ingestion) -
Acute Iron Poisoning ... caustic mucosal injury ... Abdominal pain, nausea ... caustic bowel injury ... #Toxicology #Diagnosis
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... 5) History of acute ... #Toxicology #diagnosis ... #management #Treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... /HDS treatments ... for alternative causes ... dechallenge • Acute ... #Diagnosis #Algorithm
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... antipsychotic drugs ... Clozapine is known to cause ... #Toxicity #Diagnosis ... #Pharmacology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
cytotoxic lung injury ... pleural effusions • Acute ... acute respiratory ... Exclude other causes ... #management #Toxicology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
liver or renal injury ... circulation If drugs ... before beginning treatment ... cardiac output - Acute ... peritonitis - Acute
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
abnormality, Medication/Drug ... toxicity, Metabolic ... syndrome, ADEM, Acute ... the underlying cause ... • Treatment of
Differential Diagnosis: New-Onset Seizure in the Elderly STRUCTURAL: • Stroke/TIA, Subdural hematoma, mass • Traumatic Brain Injury
Differential Diagnosis ... Traumatic Brain Injury ... (TBI) - Acute ... seizure threshold TOXICOLOGIC ... cardiovascular causes
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