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causes acidosis hematology hemolytic lactate algorithm criticalcare medications typea typeb acute agitation aki chronic conjugated delirium elevation erythematosus extravascular fatigue
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
- Classification ... and Differential ... Diagnosis Type ... delivery: Hypoxemia, Anemia ... #Differential #
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... in Hemolytic Anemia ... medications #Hemolytic #Anemia ... #differential # ... diagnosis #pharmacology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Deficiency • Drugs ... #MCV #Classification ... #Differential #
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... Utilization (VO2) • Drugs ... Acidosis #types #differential ... #diagnosis #pathophysiology ... #classification
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... AIHA: warm, cold, drug ... #Differential # ... #classification
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Shock, Severe Anemia ... Utilization (VO2) • Drugs ... #Acidosis #Differential
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue - Differential ... Diagnosis Algorithm ... Hematologic • Anemia ... Myasthenia Gravis Pharmacologic ... #Diagnosis #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... infection) - Drugs ... (Beta lactam antibiotics ... Extravascular #Causes #differential ... #anemia
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... (eg, hemolytic anemias ... Crigler-Najjar syndrome, drug ... #diagnosis #conjugated ... #unconjugated #differential
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