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causes anemia acidosis hematology medications hemolysis lactate table typea typeb acute aki algorithm conjugated deficiency druginduced elevation extravascular g6pd high
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... infection) - Drugs ... (Beta lactam antibiotics ... Extravascular #Causes #differential ... #diagnosis #hematology
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
- Classification ... and Differential ... Diagnosis Type ... #Differential # ... Diagnosis #TypeA
Drugs Implicated in Hemolytic Anemia • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
Drugs Implicated ... in Hemolytic Anemia ... #medications #Hemolytic ... #Anemia #differential ... #diagnosis #pharmacology
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis ... Utilization (VO2) • Drugs ... Acidosis #types #differential ... #diagnosis #pathophysiology ... #classification
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... AIHA: warm, cold, drug ... #Diagnosis #causes ... #classification
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology # ... differential #diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Deficiency • Drugs ... #Anemia #MCV #Classification
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... production (eg, hemolytic ... anemias, hemolytic ... #diagnosis #conjugated ... #unconjugated #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... Diagnosis The ... circulation If drugs ... Alcohol • Type B2: Drugs ... #typea #typeb #classification
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... telangiectasia) Unknown Drug ... Schistosomiasis - Chronic hemolytic ... Hypertension #PHTN #Classification ... #Diagnosis #Differential
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