26 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... Pathophysiology #Pharmacology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Injury • Pre-Renal ... Glomerular Disease: Drug ... @kdjhaveri #DrugInduced ... #differential #diagnosis
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
causing Acute Kidney ... sphincter tone: • Opiates ... decongestants) • Any drug ... #Drugs #pharmacology ... #differential #diagnosis
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Causes of Acute Kidney ... Injury ( AKI ) ... tubular necrosis • Drugs ... nephritis • Drugs ... /phimosis #Diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... - Differential Diagnosis ... Infection-mediated, Drug-induced ... #AKI #Acute #Kidney ... #Diagnosis #nephrology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
InjuryDrug ... 24-72 hours of drug ... particularly underlying renal ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
causes of Acute Kidney ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #nephrology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Skin involvement, Kidney ... exposure to HDS, drugs ... non-essential drug ... hepatitis #DILI #DrugInduced
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - ... Injury (AKI) - ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... , urinalysis, renal ... Avoiding nephrotoxic drugs ... appropriate) #Acute #Kidney ... #Injury #AKI #Differential