14 results
Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... #Medications #Pharmacology ... #Pathophysiology ... #Drugs #Agents ... #COX #GIIbIIIa
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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acid pathway and drugs ... #Pharmacology #Pathophysiology ... ArachidonicAcid #Pathways #COX ... Text: Clinical Pharmacology
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... AKI #Nephrology #Pathophysiology ... #Pharmacology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Drug-induced edema ... blood vessels Drug-induced ... #Differential #Pharmacology ... #Pathophysiology
Addictions: Pathogenesis

Mesolimbic Dopaminergic Pathway:
 • Dopaminergic neurons in Ventral Tegmental Area (VTA) in midbrain under continuous
stimuli (food, sex, drugs ... decision making) • Drug-induced ... use • Chronic drug ... #Addiction #Pathophysiology ... #Psychiatry #Mesolimbic
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
- Rare unless co-ingestion ... Benzodiazepines #Psychiatry ... #Pharmacology # ... pathophysiology
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
Drug-Induced Seizures ... Cocaine, Camphor, CO ... Kat_Watson #Drug ... #Induced #Seizures ... #Differential #Pharmacology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... induced acute kidney ... 24-72 hours of drug ... of vancomycin induced ... Vancomycin #AKI #pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology #
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
cytotoxic reaction to drug ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology