22 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... pathology (low level ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Transaminase Levels ... Liver #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #differential #Diagnosis ... #Management #gastroenterology ... gastroenterology #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... conditions Diagnosis ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
• Increased levels ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis ... #LFTs
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... function tests (LFTs ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
decr of C3 and C4 levels ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology #
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... factor activity levels ... Chronic Management ... #Management #treatment ... #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Hepatocellular Level ... liver #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
time • Reduced levels ... II • Reduced levels ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology