21 results
Stress Dose Steroids - Indications and Dosing

SUPPRESSED HPA AXIS:
 prednisone >20mg/day x 3 weeks or more
prednisone >20mg/day ... Indications #Dosing #Endocrinology ... #Diagnosis #Management ... #Pharmacology
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
Blood Cultures - Did ... they receive antibiotics ... Decreased yield due to antibiotic ... therapy - Number one cause ... BloodCultures #Diagnosis
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Januvia) - Once/day ... not definitively cause ... DPP4 #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm
ACTH-Dependent (Secondary):
 • Pituitary Dysfunction
 • Hypothalamic Dysfunction
ACTH-Independent (Primary):
Causes of Adrenal ... - Differential Diagnosis ... vein thrombosis), DIC ... #Algorithm #Causes ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... daily → 1000mg 2x/day ... agent • Does not cause ... #Metformin #Pharmacology ... DM2 #diabetes #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Byetta) - Twice/day ... not definitively cause ... Receptor #Agonists #Pharmacology ... DM2 #diabetes #endocrinology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... intravascular coagulation (DIC ... Drugs (Beta lactam antibiotics ... Extravascular #Causes
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
, venlafaxine Antibiotics ... #Medications #Causes ... #differential #diagnosis ... #pharmacology #
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... Constipation, Dry ... Pathophysiology #Pharmacology ... SideEffects #Psychiatry #Diagnosis
Drug-Induced Seizures - OTIS-CAMPBELL

O - Organophosphate, oral hypoglycemics, opioid
T - TCA, theophylline
I - Isoniazid, Insulin
S -
anticholinergics, amantadine, antibiotics ... Seizures #Medication #Causes ... #Differential #Pharmacology ... #Diagnosis #OTISCAMPBELL