27 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Malaise, bleeding, infections ... : Blast crises ... -> Invade Skin: ... Leukemia #Hematology #Oncology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... - Differential ... Neoplastic: • Squamous ... Cryoglobulinemia Infectious ... Diagnosis #Algorithm #causes
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... old, ~10,000 new cases ... risk-stratification • Risks: infection ... Allogeneic stem cell ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Hepatomegaly • Skin ... microglobulin Treatment ... Transform to DLBCL, PML ... diagnosis #workup #oncology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Algorithm for the Management ... abnormal white blood cell ... 12 000 or <400 cells ... oral antibiotic treatment ... including those caused
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
Pain (Otalgia) - Differential ... Cholesteatoma • Basal/squamous ... cell CA • Melanoma ... the tragus to differentiate ... Otalgia #Ear #Pain #Otology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... petechiae) • Frequent infections ... • Parvovirus infection ... blood count with differential ... diagnosis #hematology #oncology
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess - Differential ... antibiotics as a cause ... Toxoplasmosis, Entamoeba Skin ... #Diagnosis #InfectiousDiseases
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... drug reaction, infection ... glucocorticoid treatment ... symptoms (eg, skin ... Disorders #Algorithm #Differential