16 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... (CVID, WAS), (neurologic ... of thrombocytopenia ... #Workup #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... child * Severe cases ... Bloodman #Pregnancy #Thrombocytopenia ... AFLP #obstetrics #hematology ... #diagnosis #table
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
transfusion • Thrombocytopenia ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Heparin Induced Thrombocytopenia ... ♀, ↑Age, ESRD Pathophysiology ... hypercoagulable state ... consumption → thrombocytopenia ... Management #Treatment #Hematology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
, asthenia • Neurologic ... Systemic effect -> Nausea ... alopecia (unusual), thrombocytopenia ... #SideEffects #Pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
considered in all cases ... Heparin-induced thrombocytopenia ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
the most common cause ... to read but able ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... ↑ sIL-2R >2400 Ul ... Drugs, Unknown cause ... 100 mg/m2) : in case ... treatment #summary #rheumatology