17 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
pharmacology ... #pharmacology # ... inopressors #diagnosis ... #management #comparison ... #table
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential Diagnosis ... Sickle cell • Unstable ... #Algorithm #Causes ... #Hematology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
set of symptoms) caused ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Drugs 5. ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
- Differential Diagnosis ... findings based on cause ... adrenal crisis, drugs ... #Differential #Diagnosis ... #table #comparison
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... ↑ sIL-2R >2400 Ul ... immune deficiency, Drugs ... , Unknown cause ... treatment #summary #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... life-threatening causes ... #Presentation #comparison ... #Table #Diagnosis