40 results
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA ... Differential Diagnosis Table ... - Drug-induced TMA ... Microangiopathy #TMA ... #hematology #differential
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Treatment of Thrombotic ... TTP from other TMA ... HUS) Treatment ... #rheumatology # ... hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-mitochondrial (AMA ... Endomyseal antibody (EMA ... diseases #diagnosis #table ... #rheumatology #
Asthma	and	Status	Asthmaticus
#Pharm #Management #Peds #Asthma #Status #Asthmaticus #Treatment #Options #Table #PEMSource
Asthma and Status ... #Peds #Asthma #Status ... #Asthmaticus #Treatment ... #Options #Table
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
fibrin clot - Treatment ... Maximum Amplitude (MA ... minutes after MA ... /MCF - Treatment ... #coagulation #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... Comparison #Diagnosis #Table ... #Hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
prolonged -> FFP If MA ... Management #Diagnosis #Hematology ... Thromboelastogram #Treatment
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
-> FFP - If MA ... TEG #Management #treatment ... #diagnosis #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Visceral, DIC, TMA ... diagnosis #management #treatment ... #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
effect following treatment ... or hyposplenic states ... Algorithm #Causes #Hematology