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Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... Myelofibrosis Stem ... Algorithm #Causes #Hematology
Hematopoietic Stem Cell Lineage #Hematopoietic #StemCell #Lineage #hematology #diagnosis #maturation
Hematopoietic Stem ... StemCell #Lineage #hematology
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Abnormal APTT Step ... Step 2: Is the Patient ... Thrombin Inhibitor) Step ... Step 4: Mixing Studies ... prolonged #diagnosis #hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
solid organ or stem ... differential #diagnosis #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider stem ... management #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
• Allogeneic stem ... Management #treatment #hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
vasculitis • Hematologic ... criteria for 1) hematologic ... hematopoietic stem ... Autoinflammatory #Somatic #rheumatology
Erythropoiesis (RBC Production and Maturation) Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
hematopoietic stem ... Production #Maturation #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Hematopoietic stem ... #Indications #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. Step 1: In the patient with
Step 1: In the patient ... Step 2: If TS is ... Step 3: All patients ... including liver and hematologic ... diagnosis #management #hepatology
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