45 results
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased renal ... hypertrophy • Sodium ... #Mechanisms #pathophysiology ... #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
- Differential Diagnosis ... Algorithm Hypovolemia ... Hypothyroidism, Stress ... #Algorithm #Causes ... #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential Diagnosis ... Algorithm - Utilizing ... Osmolarity 3) Urine Sodium ... High Uric Acid → renal ... #Algorithm #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Algorithm Hypovolemic ... cirrhosis, nephrotic syndrome ... Stress, Nausea, ... #Algorithm #diagnosis ... #nephrology #sodium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
- Differential Diagnosis ... Algorithm Extra-renal ... loss (Diarrhea) Renal ... #Algorithm #causes ... potassium #low #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Workup Algorithm ... mOsm/kg - Implies renal ... , Cushing syndrome ... #nephrology #sodium
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
- Differential Diagnosis ... Algorithm Overfill ... (Increased renal ... sodium retention ... Acute Respiratory Distress
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... • nephrotic syndrome ... #Workup #Algorithm ... #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table