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management differential hematology algorithm cardiology causes disease infectiousdiseases mds myelodysplastic syndromes abscess activation amiodarone anemia antibiotic aplastic apml bronchiectasis calcium
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
NMS, serotonin syndrome ... Immunocompromise Treatment ... (daptomycin in lungs ... • Secondary to Treatment ... thrombophlebitis), HAP, Blood stream
Right-Sided Heart Failure - Differential Diagnosis Algorithm Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
- Differential Diagnosis ... • Diffuse Lung ... Acute Respiratory Distress ... Syndrome ... • Chronic Lung Infection
Streptococcal Toxic Shock Syndrome (STSS) Complication of invasive GAS disease characterized by shock & MOF → occurs
Streptococcal Toxic Shock Syndrome ... kidneys, liver, lung ... Treatment Strategy ... day 2 + 3 BIDMC Infectious ... #STSS #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... : Infection (sepsis ... #oncology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... polymicrobial infection ... hemorrhage • Treatment ... Aeruginosa - Strep ... #Abscess #pulmonary
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... in the adjacent lung ... of the affected lung ... parenchyma Diagnosis ... mycobacteria Treatment
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... • Shrinking lung ... #differential #diagnosis ... #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... confirm DAH, r/o infection ... sparing of the lung ... #management #treatment
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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