55 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... #CNS #neurology ... #rheumatology # ... #management #treatment
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Anti-cardiolipin (aCl ... #diagnosis #associations ... #table
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... (APS) APS is a ... to be present Treatment ... #APS #diagnosis ... #management #anticoagulation
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... #TLS #diagnosis ... #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cell transplant is ... only curative treatment ... #Management #treatment ... #hematology #oncology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
rare, Malar rash is ... thiazidic, PPI, ACE ... #comparison #table ... #rheumatology # ... diagnosis #management
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
ISCHEMIA Trial - Management ... This is not for ... acute coronary syndrome ... (ACS) evaluation ... Angina #ChestPain #Diagnosis
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Body Myositis (IBM ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Clubbing - IBD ... Spondyloarthropathy-IBD ... - SLE Neurologic ... #differential #diagnosis ... #rheumatology