24 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Algorithm Infectious ... Inflammatory • Systemic Lupus ... #Algorithm #Causes ... #Hematology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... nodules, lupus ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... #differential #diagnosis ... #algorithm #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Evolution: Chronic disease ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic lupus ... life-threatening causes ... #Presentation #comparison ... #Table #Diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... lesions • Dermal/subcutaneous ... Differential Diagnosis ... #rheumatology