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diagnosis differential algorithm clinical classification management oncology rash skin intravascular iron mcv secondary thrombocytosis acidosis aplastic approach arterial canimorsus capnocytophaga
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
disorders • Celiac disease ... Damage: • Post-op surgery ... effect following treatment ... anemia #Thrombocytosis ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... • Folate Deficiency ... Diagnosis #Algorithm #Causes ... #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... bleed, Epistaxis, Surgery ... Structural: Celiac disease ... #Anemia #Differential ... Algorithm #ferritin #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... , Folate deficiency ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... • Pancreatic Disease ... • Liver Disease ... #Hematology
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Loss (without anaemia ... gastritis, Bariatric surgery ... Edema, Celiac disease
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Disease • Marrow ... Diagnosis #Algorithm #Causes ... #Hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
secondary to Systemic Diseases ... Spoon-shaped • Iron deficiency ... anemia Onycholysis ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... necrosis) • VIT K deficiency ... • Liver disease ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... Diagnosis #Algorithm #hematology
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