119 results
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Hormones Acting ... Their Site of Action ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Decreased Aldosterone Synthesis ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium
Steroid Synthesis Pathway

Dr. Caoimhe Costigan @CaoimheCostigan

#Steroid #Synthesis #pathophysiology #algorithm #endocrinology
Steroid Synthesis ... CaoimheCostigan #Steroid #Synthesis ... #pathophysiology ... #algorithm #endocrinology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
(Losartan) • Synthesis ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #potassium
Insulin and Glucagon Pathophysiology
Insulin: 
 • Glucose utilization (Glycolysis)
 • Glucose storage (Glycogenesis)
 • Fat synthesis
Insulin and Glucagon Pathophysiology ... Glycogenesis) • Fat synthesis ... tissues Glucagon Actions ... : • Glucose synthesis ... Insulin #Glucagon #Pathophysiology
Constipation - Differential Diagnosis Algorithm
Diet/Lifestyle
 • Fibre
 • Calories
 • Fluid
 • Exercise
 • Psychosocial
Medications
 •
Constipation - Differential ... Diagnosis Algorithm ... Medications • Neurally Active ... Aluminum, Calcium, Potassium ... #Diagnosis #Algorithm
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Hypokalemia - Differential ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Hepatic Bile Acid Synthesis ... sequestration #pathophysiology
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Prostaglandin Synthesis ... prostaglandin synthesis ... , leaving actions ... #Pharmacology #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... GI losses (NG suction ... #Diagnosis #Algorithm ... nephrology #low #potassium