263 results
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
phosphatase: • Synthesis ... due to increased synthesis ... clearance - AP synthesis ... Chemistry #Tests #Laboratory
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Decreased albumin synthesis ... Hepatic #Hepatology #Laboratory
Acute-phase Reactants Synthesized in the Liver 
Positive acute-phase reactants (concentrations increase with acute inflammation)
 - Immune-related
Synthesized #Liver #Synthesis ... pathophysiology #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
venipuncture sites Laboratory ... : - Impaired synthesis
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
dialyzer membranes synthetic ... FalsePositives #Laboratory
Primary Adrenal Insufficiency:
 • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
stimulation test - Synthetic ... Insufficiency #Evaluation #laboratory
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
PTU) • Blocks synthesis ... Methimazole • Blocks synthesis ... Administer only after synthetic
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Action Cell Wall Synthesis ... Glycopeptides Protein Synthesis ... Folic Acid Synthesis ... Metronidazole mRNA Synthesis
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Inhibit Cell Wall Synthesis ... Inhibit Protein Synthesis ... Inhibit Protein Synthesis ... Inhibit Nucleic Acid Synthesis ... Inhibits Folate Synthesis
Functions of the Liver

Storage 
Degradation 
Metabolism 
Synthesis 

#Pathophysiology #Functions #Liver #Hepatology #Synthesis #Storage #Metabolism
Metabolism Synthesis ... Liver #Hepatology #Synthesis