10 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... Using the GFR clock ... #Diagnosis #Nephro ... #CKD #EGFR #Staging
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
, AKD Acute Kidney ... • GFR < 60 ml/min ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR ... #renal #diagnosis
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
perfusion of remaining nephrons ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
as a marker of kidney ... accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... CockcroftGault #EGFR
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Criteria HRS-AKI (Acute ... haematuria, Normal renal ... months - eGFR ... ascites • HRS-CKD ... - eGFR < 60ml
Chronic Kidney Disease (CKD):

Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Chronic Kidney Disease ... Initial dips in eGFR ... GFR reductions of ... for people with acute ... #CKD #eGFR #Kidney
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic Kidney ... function (eGFR ... 3 months Pre-Renal ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
t-PA, heparin Acute ... acidosis, DKA Kidney ... Disease: • AKI, CKD ... Increased Renal ... Hypoparathyroidism, Acromegaly, FGFR
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... tubule in the nephron