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diagnosis acute aki algorithm differential biomarkers calculation chronic clearance cockcroftgault complications creatinine definitions equations formulas gout hyperkalemia hyperuricemia injury k
Definitions of AKI, CKD, AKD Acute Kidney Injury (AKI): • Increase in SCr by 2 50% within
• GFR < 60 ml/min ... OR • GFR < 60 ... • Decrease in GFR ... • GFR ≥ 60 ml/min ... #nephrology #acute
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... , CKD • Medications ... nephroprotective ↓ in GFR ... , CKD • Obesity ... #laboratory #nephrology
Effects of Prostaglandins and NSAIDs on the Kidney Effects of Prostaglandins on the Kidney: • The vasodilatory
is increased in CKD ... prolonged NSAID use in CKD ... with GFR > 30 and ... avoidance with GFR ... #renal #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD ... KidneyDisease #Nephrology
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
as a marker of kidney ... accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... #Diagnosis #Nephrology
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 Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... myoglobin • Myeloma ... Differential #Diagnosis #nephrology ... #causes
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... Release of purine bases
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
esp w oliguria / GFR ... Labs: BMP (Assess GFR ... only if no clear cause ... status to improve GFR ... sufficient if intact GFR
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