13 results
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... as a proxy for kidney ... Using the GFR clock ... #Diagnosis #Nephro ... #CKD #EGFR #Staging
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
, AKD Acute Kidney ... • GFR < 60 ml/min ... • AKI, OR • GFR ... • Decrease in GFR ... • GFR ≥ 60 ml/min
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI, CKD ... nephroprotective ↓ in GFR ... Cystatin C: • AKI, CKD ... hyperthyroidism ↓ eGFR
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
perfusion of remaining nephrons ... maintaining baseline GFR ... setting of modest GFR ... with GFR > 30 and ... avoidance with GFR
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Kidney Disease ... function (eGFR ... ) • Multiple myeloma ... Hyperphosphatemia #CKD
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
months - eGFR ... - No other cause ... ascites • HRS-CKD ... - eGFR < 60ml ... - No other cause
Effects of a Low-Protein, Low-Salt Diet on the Afferent Arteriole. A lower intake of dietary protein
#Pathophys #Nephro ... #CKD #LowProteinDiet ... #GFR #NEJM
Chronic Kidney Disease (CKD):

Individualize BP-lowering therapy and treatment targets in people with frailty, high risk of
Chronic Kidney Disease ... (CKD): Individualize ... Initial dips in eGFR ... GFR reductions of ... #CKD #eGFR #Kidney
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... filtration rate (GFR ... decr ability of kidneys ... tubule in the nephron ... Release of purine bases
Effect of Tolvaptan on the Estimated Glomerular Filtration Rate (GFR). #EBM #Nephro #Pharm #Tolvaptam #PCKD #PolyCysticKidneyDisease
Filtration Rate (GFR ... #EBM #Nephro #Pharm ... #Tolvaptam #PCKD