13 results
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
Prostaglandins and NSAIDs ... is increased in CKD ... use in CKD with ... Prostaglandins #NSAIDs ... #nephrology #pharmacology
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Renal #Dosing ... #Pain #Pharmacology ... #Opiates #CKD #
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
recommendations in renal ... #Medications #Pharmacology ... Dosing #Dosing #Renal ... #Impairment #CKD ... #Table #GFR #Hypoglycemics
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Renin Release: NSAIDs ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... Impaired #Potassium #Renal
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
3 months Pre-Renal ... eosinophiluria) • Drugs (NSAlDs ... ) • Multiple myeloma ... Hyperoxaluria • Hypercalcemia ... Hyperphosphatemia #CKD
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
: • CKD • Poorly ... diuretics • NSAIDs ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
: • CKD • Poorly ... diuretics • NSAIDs ... resistance Impaired Renal ... deficiency • Renal ... Type IV RTA • Renal
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
K+, ACEi/ARBs, NSAIDs ... post-hypothermia • ↓ Renal ... Excretion: - Renal ... VBG (acidosis), CK ... 15 suggests ↓ renal
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
multi-drug resistance) Renal ... syndrome • AKI/CKD ... Conn's syndrome • NSAlDs ... Hyperthyroidism • Hypercalcemia
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
disorders including hypokalemia ... Hyperthyroidism, Hypercalcemia ... Pheochromocytoma • Toxic: NSAlDs ... Renal parenchymal ... disease: CKD, acute