102 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Lysis Syndrome (TLS ... Abnormalities of TLS ... Laboratory TLS ... mg/dL Clinical TLS ... Treatment of TLS
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
lysis syndrome (TLS ... cytotoxic therapy of ALL ... TumorLysis #syndrome #TLS
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Lysis Syndrome (TLS ... TumorLysis #Syndrome #TLS
Beevor's Sign on Physical Exam

Beevor's sign is abnormal upward (cephalad) movement of the umbilicus with truncal
Beevor's Sign on ... Exam Beevor's sign ... The sign been also ... been observed in ALS ... PhysicalExam #clinical #video
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... WBC >100k, + lab signs ... leukapheresis - TLS ... Lysis #Syndrome #TLS
Tongue Fasciculations in ALS

Martín Hunter MD @interconsulta

#Tongue #Fasciculations #als #amyotrophic #lateral #sclerosis #neurology #physicalexam #clinical #video
Fasciculations in ALS ... Fasciculations #als ... physicalexam #clinical #video
Jaw-Jerk Reflex Clonus in ALS

- Neurology Pro - A DDx Tool @ProDdx

#JawJerk #Jaw #Jerk #Reflex #Clonus
Reflex Clonus in ALS ... Reflex #Clonus #ALS ... #clinical #video
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Treatment of Clinical TLS ... MatthewHoMD #TLS
Jaw Jerk Reflex - Mandibular Clonus

Seen in this patient with ALS

#Jaw #Jerk #JawJerk #Reflex #Mandibular #Clonus
this patient with ALS ... chin #clinical #video ... #physicalexam #ALS
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Lysis Syndrome (TLS ... Pathophysiology Culprits: ALL ... Burkitt, SCLC Cells all ... Lysis #Syndrome #TLS