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Important Respiratory Distress Pearls

#diagnosis #respiratory #distress #NRDS #RDS #TTN #MAS #neonatal #pediatric #adult #respiratory #adverse #effects
distress #NRDS #RDS #TTN
Preterm Infant Complications - Differential Diagnosis
Respiratory:
 • Transient Tachypnea of the Newborn (TTN)
 • Respiratory Distress
of the Newborn (TTN
Causes of Respiratory Distress in the Newborn - Differential Diagnosis Algorithm
Premature Newborn
 - Normal CXR:
of the Newborn (TTNB ... of the Newborn (TTNB
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
predisposition (TTN ... Serial TTE and close
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
Microvascular: TTP ... Athero-embolic, HTN ... Ischemia-induced: ATN
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... suggests against TTP ... pregnancy, & malignant HTN
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- TTE/liver fxn? ... Liano 1996) - ATN ... CKD— 13% (mostly ATN
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
hemolytic anemia (TTP ... eclampsia, malignant HTN
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Fragmentation - MAHA: TTP ... Valves, AS - HTN
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Microangiopathy - TTP ... implications : TTP ... confirmatory testing for TTP ... thrombocytopenic #purpura #TTP