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differential management lupus erythematosus classification systemic dermatology antibodies table algorithm ana antinuclear treatment vasculitis workup anemia causes chronic comparison criteria
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table ... #rheumatology #
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
- SLE Neurologic ... , Behçet's syndrome ... Inflammation of ear ... #differential #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... • Specific for SLE ... #Summary #diagnosis ... #rheumatology #
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... IBD • RA • SLE ... Antiphospholipid-antibody syndrome ... #differential #diagnosis ... #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... Table #Pulmonary #Rheumatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... dermatomyositis, SLE ... #differential #diagnosis ... #dermatology #oncology ... #clinical #skin
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Associated - SLE ... #hematology #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Neurologic-Centered ... Ig deposition disease ... #hematology #oncology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... Features: alveolitis, ear ... thromboembolic disease ... Autoinflammatory #Somatic #rheumatology
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