18 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... or symptoms of ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... Diagnosis Framework ... (>1000): • DILI ... Drug-induced liver injury ... #Diagnosis #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... abnormality vs bone Bili ... Transaminitis #diagnosis ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... hepatocellular injury ... Interpretation #diagnosis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... → liver test abnormalities ... Differential Diagnosis ... #hepatology #algorithm ... Transaminitis #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... extrahepatic source - Tests ... #algorithm #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
algorithm. ... suspicious clinical symptoms ... /signs should be ... #LFTs #Abnormal ... #Algorithm #Hepatology
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
and Management ... Tropheryma whipplei Symptoms ... and Signs: 1. ... positive T. whipplei test ... #algorithm #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
quantify renal injury ... anti-GBM) Other tests ... pericardial effusion) • PFTs ... or serologies + symptoms ... #management #treatment
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
bronchial wall injury ... inflammation Symptoms ... Nasal polyps and signs ... parenchyma Diagnosis ... #differential #diagnosis