20 results
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
- SEROSITIS - RENAL ... - NEUROLOGIC ... determined by Positive test ... Direct Coombs’ test ... #Diagnosis #Rheumatology
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Diabetes Insipidus Workup ... Uglucose Step #3 ... & desmopressin test ... Hypernatremia #Management ... Algorithm #Sodium #nephrology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease & renal ... Summary #diagnosis #rheumatology ... #management
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
if < 200ng/mL Best ... Special cases (e.g. renal ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
of Membranous Lupus ... to treat extra-renal ... #Membranous #Lupus ... Algorithm #Treatment #management ... #nephrology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... or 0.5 g/day → renal ... #rheumatology # ... nephrology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... clinically suspected, tests ... Anti-DFS70 0-3% ... erythematosus #diagnosis #rheumatology ... #table #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... hyperglobulinemia (3) ... Arthritis #laboratory #workup ... diagnosis #testing #Rheumatology
HIV PrEP (Pre-Exposure Prophylaxis) - Truvada 

HIV Pre-Exposure Prophylaxis (PrEP) is available in the form of
single once-daily tablet ... clinician every 3 ... Renal function should ... after the first 3 ... PrEP actually works